A SIMPLE KEY FOR METHADONE HYDROCHLORIDE SYNTHESIS UNVEILED

CYP2B6 is A very powerful CYP enzyme involved in the metabolism of S-methadone also to an extent, R-methadone. The expression of CYP2B6Opioids (Combined Agonist / Antagonist): Could diminish the analgesic effect of Opioid Agonists. Management: Search for alternatives to combined agonist/antagonist opioids in patients getting pure opioid agonists, a